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Cresolphthalein (o-) Indicator 0.04%

w/v in Denatured Ethanol
Item # C1027
Weight N/A
Dimensions N/A
Size(s)

1L, 120mL, 500mL, 3.8L

Manufacturer

Packaging Type

Poly, Poly Gallon, Poly w/ Fliptop

Safety Data Sheet View/Download SDS
Sample COA View/Download Sample COA

pH 8.2 (colorless) - pH 9.8 (violet) Ready-to-use reagent. Prepared with ACS reagent grade Cresolphthalein and Reagent Alcohol. Suitable for laboratory use.

Product Overview

o-Cresolphthalein, also known as ortho-Cresolphthalein, is a phenolphthalein-type pH indicator and metal complexation reagent widely used in clinical and analytical chemistry. It exhibits a distinct color change from colorless to reddish-purple over the pH range of 8.2 to 9.8, making it suitable for monitoring alkaline titrations.

This compound is best known for its use in the o-Cresolphthalein Complexone (OCPC) method for the colorimetric determination of calcium in biological fluids. In this application, o-Cresolphthalein forms a violet-colored complex with calcium ions in alkaline solution, allowing accurate photometric quantification in clinical assays and diagnostic kits.

Key Features:

  • pH transition range: 8.2 (colorless) to 9.8 (reddish-purple)
  • Forms a violet complex with calcium under alkaline conditions
  • Highly specific for calcium in the presence of magnesium with proper masking
  • Available in powder or concentrated solution form
  • Stable for routine clinical and laboratory use

Applications:

  • Colorimetric calcium determination in serum, plasma, and urine
  • pH indication in alkaline titrations and buffer systems
  • Diagnostic reagent in clinical analyzers and assay kits
  • Research involving mineral metabolism and calcium homeostasis

o-Cresolphthalein is a critical reagent in both clinical diagnostics and chemical analysis, valued for its high sensitivity, specificity for calcium, and clear visual and spectrophotometric response.

 

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